Androgenetic alopecia affects a significant part of the population, impacting up to 80% of men and nearly half of women over the course of their lives*

What is Kyoh®?
Kyoh® is a scientifically developed extract obtained from the leaves of Eruca sativa, characterized by a well-defined phytochemical composition and standardized to contain more than 1.5% Erucosides®, Pharmactive’s proprietary complex of flavonol glycosides naturally occurring in rocket leaves. Using HPLC analytical methods, Kyoh® delivers a consistent flavonol glycoside profile ranging from 1.5% to 3.0%, primarily composed of quercetin, kaempferol, and isorhamnetin derivatives, supporting high batch-to-batch uniformity and quality consistency.
The flavonol compounds naturally present in Kyoh® have been investigated for their antioxidant properties and their involvement in biological processes related to follicular activity, including pathways associated with cellular defense and hair follicle support*.
The quality profile of Kyoh® is supported by controlled European sourcing practices, careful raw material selection, and a proprietary manufacturing process developed to maintain the stability, integrity, and reproducibility of its characteristic phytochemical profile.
How does it work?
The following mechanisms have been investigated for Kyoh®:

Why Kyoh®?
Developed to meet the evolving demand for next-generation beauty-from-within solutions.

Follicle-focused biological research
Kyoh® was assessed in a recent in vitro investigation using cultured human dermal papilla cells, a well-recognized model in hair follicle biology research.
The study findings showed increased expression of VEGF and FGF7, signaling pathways involved in follicular physiology and hair follicle activity*. Kyoh® also demonstrated activation of NRF2-associated antioxidant pathways related to cellular defense mechanisms and protection against oxidative stress*.
Additionally, the extract supported dermal papilla cell activity, highlighting its potential as a targeted botanical ingredient for next-generation beauty-from-within formulations focused on follicle health and hair wellness.

Controlled European sourcing
Kyoh® is manufactured from selected Eruca sativa cultivated in Europe under carefully managed agricultural conditions aimed at maintaining high standards of raw material quality and consistency.
The leaves are collected at a specific stage of development to help preserve their naturally occurring flavonol glycosides, including the compounds standardized as Erucosides®*.
Together with Pharmactive’s proprietary extraction and analytical technologies, this sourcing approach supports traceability, batch-to-batch consistency, and a well-characterized phytochemical profile suitable for advanced nutricosmetic applications.
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Non-GMO.
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Non-irradiated.
Our certifications and awards
(*)References available upon request
Disclaimer
(*) These statements have not been evaluated by the European Food Safety Authority (EFSA) or other pertinent Regulatory Authority. This product is not intended to diagnose, treat, cure or prevent any disease.










