Improve mood, relieve stress, support relaxation and enhance sleep*†

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Maintain a positive mood*†

Induce relaxation, improve occasional stress, anxiety, and tension*†

Sleep better to address occasional sleeplessness*†

1 million people worldwide benefit from affron to maintain a positive mood and mental balance every day

What is affron?

Affron is a premium saffron ingredient standardized to 3.5% Lepticrosalides, by HPLC, a complex of bioactive compounds responsible for the beneficial properties and organoleptic properties of affron™*†. It is backed by 6 human clinical studies that have shown to improve mood in healthy consumers with occasional stress and anxiety, and to improve sleeplessnes*†.

Affron genuine quality relies on local trusted sourcing, the selection of the Spanish species Crocus sativus L. and the exclusive and proprietary extraction process that uniquely concentrates and preserves the actives with low energy use.

How does it work?

The following main mechanisms of action of affron have been identified:

  • Inhibition of the reuptake mechanism of dopamine, norepinephrine, and serotonin, increasing the concentrations of these neurotransmitters in the synaptic cleft of neurons, thereby improving mood balance*†.
  • Antioxidant effect against the excessive oxidative stress produced during occasional anxiety or stress processes in the central nervous system*†.
  • Anti-inflammatory action in stressed neural tissue, decreasing hippocampal levels of apoptotic biomarkers and stress signal molecules*†.
Bote-Affron-WEB-USA

Why affron?

  • USA Award-winner Ingredient for Cognitive Health 2020.
  • 6 clinical studies published.
  • Proprietary extraction process AFF ON Cool-Tech, which uniquely concentrates and preserves the bioactives with lower energy use.
  • Genuine Crocus sativus L. Made in Spain.
  • Own extraction plant.
  • Lowest dosage: 28 mg/day.
  • Unique dose-response study in 128 healthy adults*†.
  • Clinically studied in adolescents*†.

affron is the most published saffron extract in the world, reaching 6M of potential audience

Proprietary extraction process: AFF ON Cool-Tech

It is a patented, low-temperature production process that creates highly concentrated affron with long-lasting actives’s stability of at least 36 months.

This technique allows us to get superior saffron Quality with less industrial processing, less energy use and zero chemicals.

Winner NutraIngredients Awards

Affron has been recognized as the Ingredient of the Year for Cognitive Function, at The NutraIngredients USA Awards, 2020.

  • Non-GMO.

  • Non-irradiated.

Our certifications and awards

(†) References available upon request

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Disclaimer

(*) These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure or prevent any disease.