Maintain a positive mood*†

Induce relaxation, improve occasional stress and tension*†

Sleep better to address occasional sleeplessness*†

1 million people worldwide benefit from affron® to maintain a positive mood and mental balance every day*

What is affron®?

Affron® is a premium saffron ingredient standardized to 3.5% Lepticrosalides, by HPLC, a complex of bioactive compounds responsible for the beneficial properties and organoleptic properties of affron®*†. It is backed by 8 human clinical studies that have shown to improve mood in healthy consumers with occasional stress and to improve occasional sleeplessnes*†.

Affron® genuine quality relies on local trusted sourcing, the selection of the Spanish species Crocus sativus L. and the exclusive and proprietary extraction process that uniquely concentrates and preserves the actives with low energy use.

How does it work?

The following main mechanisms of action of affron® have been identified:

  • Inhibition of the reuptake mechanism of dopamine, norepinephrine, and serotonin, increasing the concentrations of these neurotransmitters in the synaptic cleft of neurons, thereby improving mood balance*†.
  • Antioxidant effect against the oxidative stress produced during occasional stress processes in the central nervous system*†.
Bote-Affron-WEB-R-USA

Why affron®?

  • USA Award-winner Ingredient for Cognitive Health 2020.
  • 8 clinical studies published.
  • Proprietary extraction process AFF ON Cool-Tech, which uniquely concentrates and preserves the bioactives with lower energy use.
  • Genuine Crocus sativus L. Made in Spain.
  • Own extraction plant.
  • Lowest dosage: 28 mg/day.
  • Unique dose-response study in 128 healthy adults*†.
  • Clinically studied in adolescents*†.

affron® is the most published saffron extract in the world, reaching 6M of potential audience

Proprietary extraction process: AFF ON Cool-Tech

It is a patented, low-temperature production process that creates highly concentrated affron® with long-lasting actives’s stability of at least 36 months.

This technique allows us to get superior saffron Quality with less industrial processing, less energy use and zero chemicals.

Winner NutraIngredients Awards

Affron® has been recognized as the Ingredient of the Year for Cognitive Function, at The NutraIngredients USA Awards, 2020.

Best Practices Award 2020

We have been recognized by Frost & Sullivan, for Helping People Improve their Cognitive Functions with our Saffron-based Ingredient, Affron®.

Affron® improved mood on menopausal women.

A new, randomized, double-blind, placebo-controlled study showed that perimenopausal women taking affron® for 12 weeks experienced a reduction of 32-33% in low mood and occasional stress, without undesirable estrogenic effects.

The Fourth Frontier: Performance and sleep with affron®

Sleep has never been more relevant to sports nutrition and growth active nutrition.
The results demonstrate that affron® is efficacious at improving restorative sleep-in individuals with self-reported sleep disturbance.
On the basis that sport, and exercise, increases the risk of sleep disturbance, there is good rationale to use affron® in sports nutrition.
Affron® offers a proven, natural, and plant-based solution that is versatile to use in multiple formats and formulations.

Affron® improved sleep quality at a low dose

Affron® improved sleep quality at a low dose
A new, randomized, double-blind, placebo-controlled study provided further confirmation of the sleep-enhancing effects of 28 days of affron® supplementation at 14 mg, 1 hour before bedtime, facilitating consumer’s adherence.
By the very first time, a single dose of affron® 1 hour before sleep revealed the new possible mechanism of action influencing sleep hormones.

  • Non-GMO.

  • Non-irradiated.

Our certifications and awards

(†) References available upon request

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Disclaimer

(*) These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.